B.Pharmacy Semester 6

Semester 6 – Outline of Subjects and Units

Medicinal Chemistry III

• CNS Stimulants & Depressants
  SAR and classification of sedatives, hypnotics, antipsychotics, antidepressants

• Anticonvulsants & General Anesthetics
  Mechanism of action, classification, synthesis & SAR

• Analgesics & Anti-inflammatory Drugs
  Narcotic vs. non-narcotic agents, prostaglandin synthesis inhibitors

• Local Anesthetics & CNS Acting Drugs
  SAR, synthesis, and clinical importance

• Drugs for Neurodegenerative Disorders
  Anti-Parkinsonian, Alzheimer’s agents, and their synthesis

Pharmacology III

• Drugs Acting on CNS
  Sedatives, hypnotics, antipsychotics, antidepressants

• Antiepileptics & General Anesthetics
  Mechanism, classification, and pharmacodynamics

• Analgesics, Anti-inflammatory, Antipyretics
  Opioids and NSAIDs: MOA, ADRs, and uses

• Drugs for Neurodegenerative Disorders
  Parkinson’s, Alzheimer’s, Myasthenia gravis – current therapeutics

• Psychopharmacological Agents
  Antidepressants, anxiolytics, mood stabilizers

• CNS Stimulants & Drug Dependence
  Abuse potential, treatment approaches, withdrawal

Herbal Drug Technology

• Basic Concepts of Herbal Medicine
  Introduction to herbal pharmacopoeia, herb-drug interactions

• Herbal Formulation Development
  Tablets, syrups, cosmetics, nutraceuticals

• Standardization of Herbal Drugs
  WHO & AYUSH guidelines, contaminants, marker compounds

• Traditional Systems
  Ayurveda, Siddha, Unani: dosage forms & preparation

• Patent & Regulatory Aspects
  IPR, TKDL, new botanical drug registration

Biopharmaceutics & Pharmacokinetics

• Absorption & Distribution
  GIT variables, transport mechanisms, plasma protein binding

• Biopharmaceutical Considerations in Dosage Design
  BCS, dissolution, drug solubility & permeability

• Elimination: Metabolism & Excretion
  Hepatic metabolism (CYP450), renal clearance

• Pharmacokinetic Models
  One & two compartment models: IV bolus, infusion, oral dosing

• Non-linear Pharmacokinetics & Bioavailability
  Saturable kinetics, AUC, Cmax, Tmax, BA/BE studies

Pharmaceutical Biotechnology

• Biotechnological Drugs
  Recombinant products, monoclonal antibodies, vaccines

• Gene Therapy & Genetic Engineering
  Cloning vectors, r-DNA technology, CRISPR basics

• Immunology & Immunotherapy
  Antigens, antibodies, ELISA, hybridoma technology

• Microbial Biotechnology
  Fermentation processes, QC of biologicals

• Regulatory & Production Considerations
  Biosafety, GMP for biotech products, storage & transport

Quality Assurance

• Quality Concepts & GMP
  ICH Q series, quality by design, validation principles

• Documentation in QA
  SOPs, BMR, BPR, change control, deviation reports

• Quality Control Tests
  Finished product testing, microbiological QC

• Audits & Regulatory Affairs
  Internal/external audits, regulatory bodies (USFDA, EMA, CDSCO)

• IPR & Patents in Pharma
  Types, filing process, patentability criteria

🔖 What You’ll Get in Each Subject Page

• Unit-wise Simplified Notes – Focused on mechanism, SAR, and formulation logics

• MCQs & Numericals – Especially for Biopharmaceutics & QA

• Animations & Flowcharts – Explain gene tech, kinetics, herbal formulations

• Regulatory Summaries – Condensed ICH, GMP, patent content for easy recall

💡 Student Tip

Pair Medicinal Chemistry III with Pharmacology III for a strong neuropharmacology grasp. Then use that foundation to explore Biopharmaceutics and QA principles more effectively.

🔔 Stay Tuned

Weekly updates include video explainers, dosage calculation practice, mock tests, and high-yield charts for revision!